Verse

Ecclesiastes 4:6

A church father on this verse
The "chasing after wind," I believe, refers to the will of the soul caught up with passions. That is why a handful of virtue is better than two handfuls of wickedness, ignorance and "chasing after wind." … It is as if someone said it is better to learn contemplation of one spiritual thing than to have numerous visions…
Evagrius Ponticus, 4th c. — SCHOLIA ON ECCLESIASTES 27:4.6
Original

6Better is an handful with quietness, than both the hands full with travail and vexation of spirit.

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In context

4Again, I considered all travail, and every right work, that for this a man is envied of his neighbour. This is also vanity and vexation of spirit.

5The fool foldeth his hands together, and eateth his own flesh.

Ecclesiastes 4:6

7Then I returned, and I saw vanity under the sun.

8There is one alone, and there is not a second; yea, he hath neither child nor brother: yet is there no end of all his labour; neither is his eye satisfied with riches; neither saith he, For whom do I labour, and bereave my soul of good? This is also vanity, yea, it is a sore travail.

Read all of Ecclesiastes 4