“First of all consider why it is that many holy women in the Scriptures are related to have been barren, as Sarah herself, and now Rebekah. But also Rachel, Israel's beloved, was barren. Hanna also, the mother of Samuel, is recorded to have been barren. But also in the Gospels Elizabeth is related to have been barren.…”
Origen of Alexandria, 3th c. — HOMILIES ON GENESIS 12.1
Original
21And Isaac intreated the LORD for his wife, because she was barren: and the LORD was intreated of him, and Rebekah his wife conceived.
Modern
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In context
19And these are the generations of Isaac, Abraham’s son: Abraham begat Isaac:
20And Isaac was forty years old when he took Rebekah to wife, the daughter of Bethuel the Syrian of Padanaram, the sister to Laban the Syrian.
— Genesis 25:21 —
22And the children struggled together within her; and she said, If it be so, why am I thus? And she went to enquire of the LORD.
23And the LORD said unto her, Two nations are in thy womb, and two manner of people shall be separated from thy bowels; and the one people shall be stronger than the other people; and the elder shall serve the younger.