“Second, is a refusal from prayer of a person sinning. "Thou hast wrapped thyself with a cloud so that no prayer can pass through." Namely, regarding such sins displaying faults against prayer. Thus, Isaiah 59:2 claims: "But your iniquities have made a separation between you and your God."”
Thomas Aquinas, 13th c. — Commentary on Lamentations
Original
44Thou hast covered thyself with a cloud, that our prayer should not pass through.
Modern
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In context
42We have transgressed and have rebelled: thou hast not pardoned.
43Thou hast covered with anger, and persecuted us: thou hast slain, thou hast not pitied.
— Lamentations 3:44 —
45Thou hast made us as the offscouring and refuse in the midst of the people.
46All our enemies have opened their mouths against us.