Verse

Revelation 16:3

A church father on this verse
The blood of the sea and waters plainly indicate the killings of those encamped near the waters in land battles, as is natural.
Oecumenius, 6th c. — Commentary on Revelation
Original

3And the second angel poured out his vial upon the sea; and it became as the blood of a dead man: and every living soul died in the sea.

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In context

1And I heard a great voice out of the temple saying to the seven angels, Go your ways, and pour out the vials of the wrath of God upon the earth.

2And the first went, and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and upon them which worshipped his image.

Revelation 16:3

4And the third angel poured out his vial upon the rivers and fountains of waters; and they became blood.

5And I heard the angel of the waters say, Thou art righteous, O Lord, which art, and wast, and shalt be, because thou hast judged thus.

Read all of Revelation 16